We are located in the Department of Molecular, Cell and Developmental Biology Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
615 Charles E Young Drive South Biomedical Research Building
Lab is located in room 457
Amander's Office is room 451C
Research Program Our lab is committed to the use of embryonic and pluripotent stem cells to understand and treat diseases related to reproductive health...(more)
Germ Cells Primordial germ cells (PGCs) are the embryonic precursors of eggs and sperm. Abnormal development of PGCs can result in infertility, germ cell tumor formation, premature ovarian failure, failed in vitro fertilization or congenital abnormalities…(more)
Models
We use human and mouse embryonic stem cells and systemic mouse models to understand the molecular pathways critical for normal development of the germ cell lineage…(more)
Implications
Results from our research program have significant implications in understanding the basic biology of human embryonic stem cells, together with generation of clinically relevant tools for in vitro fertilization, identifying and treating infertility, understanding germ cell tumor development and causes of congenital abnormalities.
Our Lab is funded by the following sources: National Institutes of Health, California Institute for Regenerative Medicine, Stop Cancer, Lance Armstrong Foundation, Fuller Foundation and the UC Cancer Research Coordinating Committee.
