For Further Information
Please Contact
Amander Clark clarka@ucla.edu
Featured Paper
Find out how to use
human embryonic stem cells to form germ cells. Download PDF
We are located in the Department of Molecular, Cell and Developmental Biology Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
615 Charles E Young Drive South BSRB2 Room 457
Research Program
Our lab is interested in the molecular regulation of germ cell differentiation and function...(more)
Germ Cells
Germ cells are the precursors of eggs and sperm. Abnormal development of the germ cell lineage can result in infertility, germ cell tumor formation, premature ovarian failure, failed in vitro fertilization or congenital abnormalities…(more)
Models
We use human and mouse embryonic stem cells and systemic mouse models to understand the molecular pathways critical for normal development of the germ cell lineage…(more)
Implications
Results from our research program have significant implications in understanding the basic biology of human embryonic stem cells, together with generation of clinically relevant tools for in vitro fertilization, identifying and treating infertility, understanding germ cell tumor development and causes of congenital abnormalities.
Our Lab is funded by the following sources: National Institutes of Health, California Institute for Regenerative Medicine, Stop Cancer, Lance Armstrong Foundation.
