Alva, J.
(Post '06-07)

Alva, J.A., Zovein, A.C., Monvoisin, A., Murphy, T., Salazar, A., Harvey, N.L., Carmeliet, P., Iruela-Arispe, M.L. (2006). VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells. Dev. Dyn. 235(3):759-67.

Hellstrom, M., Phng, L.K., Hofmann, J.J., Wallgard, E., Coultas, L., Lindblom, P., Alva, J., Nilsson, A.K., Karlsson, L., Galanco, N. Yoon, K., Rossant, J., Iruela-Arispe, M.L., Kalen, M., Gerhardt, H., Getsholtz, C. (2007). DII4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 445(7129):776-80.

Bradley, M.N.
(Post '06-07)

Chen, M., Bradley, M.N., Beaven, S.W., Tontonoz, P. (2006). Phosphorylation of the liver X receptors. FEBS Lett. 580(20):4835-41.

Marathe, C., Bradley, M.N. Hong, C., Lopez, F., Ruiz de Galarreta, C.M., Tontonoz, P. (2006). The arginase II gene is an anti-inflammatory target of liver X receptor in macrophages. J. Biol. Chem. 281(43):32197-206.

Bradley, M.N., Hong, C., Chen, M., Joseph, S.B., Wilpitz, D.C., Wang, X., Lusis, A.J., Collins, A., Hseuh, W.A., Collins, J.L., Tangirala, R.K., Tontonoz, P. (2007). Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. J. Clin. Invest. 117(8):2337-46.

Molteni, V., Li, X., Nabakka, J., Liang, F., Wityak, J., Koder, A., Vargas, L., Romeo, R., Mitro, N., Mak, P.A., Seidel, H.M., Haslam, J.A., Chow, D., Tuntland, T., Spalding, T.A., Brock, A., Bradley, M., Castrillo, A., Tontonoz, P. (2007). N-Acylthiaziazolines, a new class of liver X receptor agonists with selectivity for LXRbeta. J. Med. Chem. 50(17):4255-9.

Bensinger, S.J., Bradley, M.N. Joseph, S.B., Zelcer, N., Janssen, E.M., Hausner, M.A., Shiah, R., Parks, J.S., Edwards, P.A., Jamieson, B.D., Tontonoz, P. (2008). LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell. 134(1):97-111.

Chari, S.
(Post '02-04)

Sheth, S.S., Castellani, L.W., Chari, S., Wagg, C., Thipphavong, C.K., Bodnar, J.S., Tontonoz, P., Attie, A.D., Lopaschuk, G.D., Lusis, J. (2005). Thioredoxin interacting protein deficiency disrupts the fasting-feeding metabolic transition. J Lipid Res. 46(1):123-34.

Chen, T.
(Pre '06-09)

Lee, S., Chen, T.T., Barber, C.L., Jordan, M.C., Murdock, J., Desai, S., Ferrara, N., Nagy, A., Roos, K.P., Iruela-Arispe, M.L. (2007). Autocrine VEGF signaling is required for vascular homeostasis. Cell. 130(4):691-703. PMID: 17719546

Lee, M., Chen, T.T., Iruela-Arispe, M.L., Wu, B.M., Dunn, J.C. (2007). Modulation of protein delivery from modular polymer scaffolds. Biomaterials. 28(10):1862-70. PMID: 17184836.

Zimman, A., Mouillesseaux, K.P., Le, T., Gharavi, N.M., Ryvkin, A., Graeber, T.G., Chen, T.T., Watson, A.D., Berliner, J.A. (2007). Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids. Arterioscler Thromb Vasc Biol. 27(2):332-8.

Anderson, S.M., Chen, T.T., Iruela-Arispe, M.L., Segura, T. (2009). The phosphorylation of vascular endothelial growth factor receptor-2 (VEGF-2) by engineered surfaces with electrostatistically or covalently immobilized VEGF. (Biomaterials, June 2009, Epub Ahead).

Evans, C.
(Post '03-05)

Evans, C.J., Hartenstein, V., Banerjee, U. (2003). Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell. 5(5):673-90.

Evans, C.J., Banerjee, U. (2003). Transcriptional regulation of hematopoiesis in Drosophila. Blood Cells Mol. Dis. 30(2): 223-8.

Jung, S.H. Evans, C.J., Uemura, C., Banerjee, U. (2005). The Drosophila lymph gland as a developmental model of hematopoiesis. Development. 132(11):2521-33.

Garner, O.
(Post '08-10)

Garner, O.B., and Baum, L.G. (2008) Galectin-glycan lattices regulate cell surface glycoprotein organization and signaling. Biochem. Soc. Trans. 36(6):1472-7.

Hong, C.
(Pre '03-06)

Hong, C., Tontonoz, P. (2008). Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors. Curr. Opin. Genet. Dev. 18(5):461-7.

Hummasti, S., Hong, C., Bensinger, S.J., Tontonoz, P. (2008). HRASLS3 is a PPARgamma-selective target gene that promotes adipocyte differentiation. J. Lipid Res. 49(12):2535-44.

Park, K.W., Waki, H., Villanueva, C.J., Monticelli, L.A., Hong, C., Kang, S., MacDougald, O.A., Goldrath, A.W., Tontonoz, P. (2008). Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferators-activated receptor-gamma expression and adipocyte differentiation. Mol. Endocrinol. 22(9):2038-48.

Bradley, M.N., Hong, C., Chen, M., Joseph, S.B. Wilpitz, D.C., Wang, X., Lusis, A.J., Collins, A., Hseuh, W.A., Collins, J.L., Tangirala, R.K. Tontonoz, P. (2007). Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. J. Clin. Invest. 117(8):2337-46.

Marathe, C., Bradley, M.N., Hong, C., Lopez, F., Ruiz de Galarreta, C.M., Tontonoz, P., Castrillo, A. (2006). 281(43):32197-206.

Lee, N.V.
(Post '05-06)

Lee, N.V. Rodriguez-Manzaneque, J.C., Thai, S.N., Twal, W.O., Luque, A., Lyons, K.M. Argraves, W.S., Iruela-Arispe, M.L. (2005). Fibulin-1 acts as a cofactor for the matrix metalloproteinase ADAMTS-1. J. Biol. Chem. 280(41):34796-804.

Krampert, M., Kuenzle, S., Thai, S.N., Lee, N.V., Iruela-Arispe, M.L., Werner, S. (2005). ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells. J. Biol. Chem. 280(25):23844-52.

Lee, N.V., Sato, M., Annis, D.S., Loo, J.A., Wu, L., Mosher, D.F., Iruela-Arispe, M.L. (2006). ADAMTS1 mediates the release of antiangiogenic polypeptides from TSP1 and 2. EMBO J. 25(22):5270-83.

Owusu-Ansah, E.
(Post '07-08)

Owusu-Ansah, E., Yavari, A., Mandal, S., Banerjee, U. (2008). Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint. Nat Genet. 40(3):356-61.

Romanoski, C.E.
(Pre '05-08)

Bennett, B.J., Romanoski, C.E., Lusis, A.J. (2007). Network-centered view of coronary artery disease. Expert Rev Cardiovasc Ther. 5(6):1095-103.

Sumanas, S.
(Post '04-06)

Sumanas, S., Lin, S. (2004). Zebrafish as a model system for drug target screening and validation. Drug Disc. Today: Targets 3, 89-96.

Kim, H.J., Schleiffarth, J.R., Jessurun, J., Sumanas, S., Petryk, A., Lin, S., Ekker, S.C. (2005). Wnt5 signaling in vertebrate pancreas development. BMC Biol. 3:23

Sumanas, S., Zhang, B., Dai, R., Lin, S. (2005). 15-zinc finger protein Bloody Fingers is required for zebrafish morphogenic movements during neurulation. Dev Biol. 283(1):85-96.

Sumanas, S., Jorniak, T., Lin, S., (2005) Identification of novel vascular endothelial specific genes by the microarray analysis of the zebrafish cloche mutants. Blood. 106(2):534-41.

Sumanas, S., Lin, S. (2006). Ets 1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol. 4(1):e10.

Kim, H.J., Sumanas, S., Palencia-Desai, S., Dong, Y., Chen, J.N. Lin, S. (2006). Genetic analysis of early endocrine pancreas formation in zebrafish. Mol Endocrinol. 20(1):194-203.

Tarr, P.
(Pre '04-06)

Kennedy, M.A. Barrera, G.C., Nakamura, K., Baldan, A., Tarr, P., Fishbein, M.C., Frank, J., Francone, O.L., Edwards, P.A. (2005). ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. Cell Metab. 1(2):121-31.

Baldan, A., Pei, L., Lee, R., Tarr, P., Tangirala, R.K., Weinstein, M.M., Frank, J., Li, A.C., Tontonoz, P., Edwards, P.A. (2006). Impaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcd1-/- bone marrow. Arterioscler. Thromb. Vasc. Biol. 26(10):2301-7.

Baldan, A., Tarr, P., Vales, C.S., Frank, J., Shimotake, T.K., Hawgood, S., Edwards, P.A. (2006). Deletion of the transmembrane transporter ABCG1 results in progressive pulmonary lipidosis. J. Biol. Chem. 281(39):29401-10.

Baldan, A., Tarr, P., Lee, R., Edwards, P.A. (2006). ATP-binding cassette transporter G1 and lipid homeostasis. Curr. Opin Lipidol. 17(3):227-32.

Tarr, P.T., Edwards, P.A. (2008). ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2. J Lipid Res. 49(1):169-82.

Villanueva, C.
(Post '07-09)

Park, K.W., Waki, H., Villanueva, CJ, Monticelli, L.A., Hong, C., Kang, S., MacDougald, O.A., Goldrath, A.W., and Tontonoz, P. (2008). Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferators-activated receptor-gamma expression and adipocyte differentiation. Mol. Endocrinol. 22(9): 2038-48.

Minehira, K., Young, S.G., Villanueva, C.J., Yetukuri, L., Oresic, M., Hellerstein, M.K., Farese, R.V. Jr,, Horton, J.D., Preitner, F., Thorens, B., Tappy, L. (2008). Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. J Lipid Res. 49(9):2038-44.

Chao, L.C., Bensinger, S.J., Villanueva, C.J. Wroblewski, K., Tontonoz, P. (2008). Inhibition of adipocyte differentiation by Nur77, Nurr1 and Nor1. Molecular Endocrinology. 22(12):2596-608. (PMID 18945812).

Walton, K.
(Pre '02)

Walton, K.A., Hsieh, X., Gharavi, N. Wang, S., Wang, G., Yeh, M., Cole, A.L., Berliner, J.A. (2003). Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine- mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein. J. Biol. Chem. 278(32):29661-6.

Walton, K.A., Cole, A.L., Yeh, M., Subbanagounder, G., Krutzik, S.R., Modlin, R.L., Lucas, R.M., Nakai, J., Smart, E.J., Vora, D.K., Berliner, J.A. (2003). Specific phospholipids oxidation products inhibit ligand activation of toll-like receptors 4 and 2. Arterioscler Thromb Vasc Biol. 23(7):1197-293.

Weinstein, M.
(Pre '08-11)

Gin, P., Yin, L., Davies, B.S.J., Weinstein, M.M., Ryan, R.O., Bensadoun, A., Fong, L.G., Young, S.G., and Beigneux, A.P. (2008) The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons. J. Biol. Chem. 283:29554-29562.

Davies, B.S.J., Waki, H., Beigneux A.P., Farber, E., Weinstein, M.M., Wilpitz, D.C., Tai, L., Evans, R.M., Fong, L.G., Tontonoz, P., Young, S.G. (2008) The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by PPARγ. Molecular Endocrinology 22:2496-2504.

Weinstein, M.M., Yin, L., Beigneux, A.P. Davies, B.S., Gin, P., Estrada, K., Melford, K., Bishop, J.R., Esko, J.D., Dallinga-Thie, G.M., Fong, L.G., Bensadoun, A., Young S.G. (2008) Abnormal patterns of lipoprotein lipase release into the plasma in GPIHPB1-deficient mice. J. Biol. Chem. 12:34511-34518.

Beigneux, A.P., Franssen, R., Bensadoun, A., Gin, P., Melford, K. Peter, J. Walzem, R.L., Weinstein, M.M., Davies, B.S., Kuivenhoven, J.A., Kastelein, J.J., Fong, L.G., Dallinga-Thie, G.M., Young, S.G. (2009) Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase. Arterio Thromb Vasc Biol. 29:956-962.

Yang, S.H.
(Post '07-08)

Yang, S.H., Qiao, X., Fong, L.G., Young, S.G. (2008). Treatment with a farnesyltransferase inhibitor improves survival in mice with a Hutchinson-Gilford progeria syndrome mutation. Biochim. Biophys. Acta. 1781(1-2):36-9.

Yang SH, Qiao X, Farber E, Chang SY, Fong LG, Young SG. (2008) Eliminating the synthesis of mature lamin A reduces disease phenotypes in mice carrying a Hutchinson-Gilford progeria syndrome allele. J Biol Chem. 283(11):7094-9.

Yang SH, Andres DA, Spielmann HP, Young SG, Fong LG. (2008) Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated. J Clin Invest. 118(10):3291-3300.

Davies BS, Yang SH, Farber E, Lee R, Buck SB, Andres DA, Peter Spielmann H, Agnew BJ, Tamanoi F, Fong LG, Young SG. (2009). Increasing the length of progerin's isoprenyl anchor does not worsen bone disease or survival in mice with Hutchinson-Gilford progeria syndrome. J Lipid Res. 50(1):126-34.

Davies, B.S., Fong, L.G., Yang, S.H. Coffinier, C., Young, S.G. (2009). The Posttranslational Processing of Prelamin A and Disease. Annu. Rev. Genomics Hum. Genet. [Epub ahead of print].

Fong, L.G., Vickers, T.A., Farber, E.A., Choi, C., Yun, U.J., Hu, Y., Yang, S.H., Coffinier, C., Lee, R., Yin, L., Davies, B.S. Andres, D.A., Spielmann, H.P., Bennett, C.F., Young, S.G. (2009). Activating the synthesis of progerin, the mutant prelamin A in Hutchinson-Gilford progeria syndrome, with antisense oligonucleotides. Hum Mol. Genet. 18(13): 2462-71.

Yang, S.H., Bergo, M.O., Farber, E., Qiao, X., Fong, L.G., Young, S.G. (2009). Caution! Analyze transcripts from conditional knockout alleles. Transgenic Res. 18(3):483-9.

Yoon, B.
(Pre '03-05)

Yi, S.E., LaPolt, P.S., Yoon B.S., Chen, J.Y., Lu, J.K., Lyons, K.M. (2001). The type 1 BMP receptor Bmpr1B is essential for female reproductive function. Proc. Natl. Acad. Sci. USA. 98:7994-7999.

Ivkovic, S., Yoon, B.S., Popoff, S.N., Safadi, F.F., Libuda, D.E., Stephenson, R.C., Daluiski, A., Lyons, K.M. (2003). Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development. 130(12):2779-91.

Yoon, B.S., Lyons, K.M. (2004). Multiple functions of BMPs in chondrogenesis. J. Cell Biochem. 93(1):93-103.

Yoon, B.S., Ovchinnikov, D.A., Yoshii, I., Mishina, Y., Behringer, R.R., Lyons, K.M. (2005). Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc. Natl. Acad. Sci. USA 102(14):5062-7.

Yoon, B.S., Pogue, R., Ovchinnikov, D.A., Yoshii, I., Mishina, Y., Behringer, R.R., Lyons, K.M. (2006). BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 133(23):4667-78.