Goldberg Lab Publications


News Teaching Website Research Publications Seed Institute Lab Members

Lab Pictures

Lab Movies




Lin, J.Y., Le, B.H., Chen, M., Henry, K.F., Hur, J., Hsieh, T.F., Pellegrini, M., Fischer, R.L., Harada, J.J., Goldberg, R.B. (2017) Similarity between soybean and Arabidopsis seed methylomes and loss of non-CG methylation does not affect seed development. Proc. Natl. Acad. Sci. USA, forthcoming.

[Download pdf file]

Pelletier, J.M., Kwong, R. Park, S., Le, B.H., Baden, R., Cagliari, A., Hashimoto, M., Munoz, M., Fischer, R.L., Goldberg, R.B., Harada J.J. (2017) LEC1 sequentially regulates the transcription of genes involved in diverse developmental processes during seed development. Proc. Natl. Acad. Sci. USA, 114:32, E6710–E6719. doi: 10.1073/pnas.1707957114.

[Download pdf file]

Danzer, J., Mellott, E., Bui, A.Q., Le, B.H., Martin, P., Hashimoto, M., Perez-Lesher, J., Chen, M., Pelletier, J.M., Somers, D.A., Goldberg, R.B., Harada, J.J. (2015) Down-regulating the expression of 53 soybean transcription factor genes uncovers a role for SPEECHLESS in initiating stomatal cell lineages during embryo development, Plant Physiology, 168:3, 1025-35. doi: 10.1104/pp.15.00432.

[Download pdf file]

Henry, K.F. and Goldberg, R.B. (2015) Using scarlet runner bean embryos to uncover regulatory networks controlling suspensor gene activity. Frontiers in Plant Science, 6:44. doi: 10.3389/fpls.2015.00044.

[Download pdf file]
Henry, K.F., Kawashima, T., and Goldberg, R.B. (2015)A cis-regulatory module activating transcription in the suspensor contains five cis-regulatory elements. Plant Molecular Biology, 88:3, 207-17. doi: 10.1007/s11103-015-0308-z. [Download pdf file]
Belmonte, M., Kirkbride, R.C., Stone, S.L., Pelletier, J.M., Bui, A.Q., Yeung, E.C., Hashimoto, M., Fei, J., Harada, C.M., Munoz, M.D., Le, B.H., Drews, G.N., Brady, S.M., Goldberg, R.B., and Harada, J.J. (2013) Comprehensive developmental profiles of gene activity in regions and subregions of the Arabidopsis seed. Proc. Natl. Acad. Sci. USA, 110:5, E434-44. doi: 10.1073/pnas.1222061110. [Download pdf file]
Le, B.H., Cheng, C., Bui, A.Q., Wagmeister, J.A., Henry, K.F., Pelletier, J., Kwong, L., Belmonte, M., Kirkbride, R., Horvath, S., Drews, G.N., Fischer, R.L., Okamuro, J.K., Harada, J.J., and Goldberg, R.B. (2010) Global analysis of gene activity during Arabidopsis seed development and identification of seed-specific transcription factors. Proc. Natl. Acad. Sci USA, 170:18, 8063-70. doi: 10.1073/pnas.1003530107. [Download pdf file]
Kawashima, T. and Goldberg, R.B. (2010) The suspensor: not just suspending the embryo. Trends In Plant Science 15:1, 23-30. doi: 10.1016/j.tplants.2009.11.002. [Download pdf file]

Kawashima, T., Wang, X., Henry, K.F., Bi, Y., Weterings, K., Goldberg, R.B. (2009) Identification of cis-regulatory sequences that activate transcription in the suspensor of plant embryos. Proc. Natl. Acad. Sci. USA, 106:9, 3627-32. doi: 10.1073/pnas.0813276106.

[Download pdf file]

Goldberg, R.B. (2009) The Plant Cell: 20 Years Young. Plant Cell, 21:1, 3-12. Editorial Article. doi: 10.1105/tpc.109.065888.

[Download pdf file]

Stone S.L., Braybrook S.A., Paula S.L., Kwong L.W., Meuser J., Pelletier J., Hsieh T.F., Fischer R.L., Goldberg, R.B., Harada J.J. (2008) Arabidopsis LEAFY COTYLEDON2 induces maturation traits and auxin activity: Implications for somatic embryogenesis. Proc. Natl. Acad. Sci. USA, 105:8, 3151-56. doi: 10.1073/pnas.0712364105.

[Download pdf file]

Ohr, H., Bui, A.Q., Le, H.B., Fischer, R.L., Choi, Y. (2007) Identification of putative Arabidopsis DEMETER target genes by GeneChip Analysis.Biochem. Biophys. Res. Commun., 364:4, 856-60. doi: 10.1016/j.bbrc.2007.10.092.

[Download pdf file]

Le, B.H., Wagmaister, J.A., Kawashma, T., Bui, A.Q., Harada, J.J., and Goldberg, R.B. (2007) Using Genomics to Study Legume Seed Development. Plant Physiology, 144:2, 562-74. doi: 10.1104/pp.107.100362.

[Download pdf file]

Xiao, W., Brown, R.C., Lemmon, B.E., Harada, J.J., Goldberg, R.B., and Fischer, R.L. (2006) Regulation of Seed Size by Hypomethylation of Maternal and Paternal Genomes. Plant Physiology, 142:3, 1160-68. doi: 10.1104/pp.106.088849.

[Download pdf file]
Xiao, W., Custard, K. D., Brown, R. C., Lemmon, B. E., Harada, J. J., Goldberg, R. B. & Fischer, R. L. (2006)DNA Methylation Is Critical for Arabidopsis Embryogenesis and Seed Viability. Plant Cell, 18:4, 805-14. Seed Institute Article. doi: 10.1105/tpc.105.038836. [Download pdf file]
Gehring, M., Huh, J. H., Hsieh, T. F., Penterman, J., Choi, Y., Harada, J. J., Goldberg, R. B. & Fischer, R. L. (2006) DEMETER DNA Glycosylase Establishes MEDEA Polycomb Gene Self-Imprinting by Allele-Specific Demethylation. Cell, 124:3, 495-506. Seed Institute Article. doi: 10.1016/j.cell.2006.12.034. [Download pdf file]
Braybrook, S. A., Stone, S. L., Park, S., Bui, A. Q., Le, B. H., Fischer, R. L., Goldberg, R. B. & Harada, J. J. (2006) Genes Directly Regulated by LEAFY COTYLEDON2 Provide Insight Into the Control of Embryo Maturation and Somatic Embryogenesis. Proc. Natl. Acad. Sci. USA, 103:9, 3468-73. Seed Institute Article. doi: 10.1073/pnas.0511331103. [Download pdf file]
Yamagishi, K., Nagata, N., Yee, K. M., Braybrook, S. A., Pelletier, J., Fujioka, S., Yoshida, S., Fischer, R. L., Goldberg, R. B. & Harada, J. J. (2005) TANMEI/EMB2757 Encodes A WD Repeat Protein Required for Embryo Development in Arabidopsis. Plant Physiol., 139:1, 163-73. Seed Institute Article. doi: 10.1104/pp.105.060467. [Download pdf file]
Sanders, P.M., Bui, A.Q., Le, B.H., Goldberg, R.B. (2005) Differentiation and Degeneration of Cells That Play a Major Role in Tobacco Anther Dehiscence. Sex. Plant. Reprod, 17:5, 219-41. doi: 10.1007/s00497-004-0231-y. [Download pdf file]
Ohto, M.A., Fischer, R.L., Goldberg, R.B., Nakamura, K., and Harada, J.J. (2005) Control of Seed Mass by APETALA2. Proc. Natl. Acad. Sci. USA, 102:8, 3123-3128. doi: 10.1073/pnas.0409858102 [Download pdf file]
Goldberg, R.B. Field of Dreams: Science Makes Exciting Ag Advances, but "Natural" Naysayers Stand in Way. Commentary originally appeared in the Daily News of Los Angeles (CA) on December 5, 2004. [Download pdf file]
Choi, Y., Harada, J.J., Goldberg, R.B., Fischer, R.L. (2004) An Invariant Aspartic Acid in the DNA Glycosylase Domain of DEMETER is Necessary for Transcriptional Activation of the Imprinted MEDEA Gene. Proc. Natl. Acad. Sci. USA, 101:19, 7481-86. Seed Institute Article. doi: 10.1073/pnas.0402328101. [Download pdf file]
Xiao, W., Gehring, M., Choi, Y., Margossian, L., Pu, H., Harada, J.J., Goldberg, R.B., Pennell, R.I., Fischer, R.L. (2003) Imprinting of the MEA Polycomb Gene is Controlled by Antagonism Between MET1 Methyltransferase and DME Glycosylase. Dev Cell., 5:6, 891-901. Seed Institute Article. doi: 10.1016/S1534-5807(03)00361-7. [Download pdf file]
Lee, H., Fischer, R.L., Goldberg, R.B., Harada, J.J. (2003)  Arabidopsis LEAFY COTYLEDON1 Represents a Functionally Specialized Subunit of the CCAAT Binding Transcription Factor. Proc. Natl. Acad. Sci. USA, 100:4, 2152-56. Seed Institute Article. doi: 10.1073/pnas.0437909100. [Download pdf file]
Kwong, R.L., Bui, A.Q., Lee, H., Kwong, L.W., Fischer, R.L., Goldberg, R.B. , and Harada J.J. (2003) LEAFY COTYLEDON1-LIKE Defines a Class of Regulators Essential for Embryo Development. Plant Cell, 15:1, 5-18. Seed Institute Article. doi: 10.1105/tpc.006973. [Download pdf file]
Choi, Y., Gehring, M., Johnson, L., Hannon, M., Harada, J.J., Goldberg, R.B., Jacobsen, S.E., and Fischer, R.L. (2002) DEMETER, a DNA Glycosylase Domain Protein Is Required for Endosperm Gene Imprinting and Seed Viability in Arabidopsis.Cell, 110:1, 33-42. Seed Institute Article. doi: 10.1016/S0092-8674(02)00807-3 [Download pdf file]
Apuya, N.R., Yadegari, R., Fischer, R.L., Harada, J.J., and Goldberg, R.B. (2002) RASPBERRY3 Gene Encodes a Novel Protein Important for Embryo Development. Plant Physiology, 129:2, 691-705. doi: 10.1104/pp.004010. [Download pdf file]
Weterings, K., Apuya, N. R., Bi, Y., Fischer, R. L., Harada, J. J., and Goldberg, R. B. (2001) Regional Localization of Suspensor mRNAs During Early Embryo Development.Plant Cell, 13:11, 2409-25. Cover Article. Seed Institute Article. doi: 10.1105/tpc.010326. [Download pdf file]
Kinoshita, T., Harada, J. J., Goldberg, R. B., and Fischer, R. L. (2001) Polycomb Repression of Flowering During Early Embryo Development. Proc. Natl. Acad. Sci. USA, 98:24, 14156-61. Seed Institute Article. doi: 10.1073/pnas.241507798. [Download pdf file]
Stone, S.L., Kwong, L. W., Yee, K. M., Pelletier, J., Lepiniec, L., Fischer, R. L., Goldberg, R. B., and Harada, J. J. (2001) LEAFY COTYLEDON2 Encodes a B3 Domain Transcription Factor That Induces Embryo Development.  Proc. Natl. Acad. Sci. USA, 98:20, 11806-11.  Seed Institute Article. doi: 10.1073/pnas.201413498. [Download pdf file]
Yadegari, R., Kinoshita, T., Lotan, O., Cohen, G., Katz, A., Choi, Y., Katz, A., Nakashima, K., Harada, J. J., Goldberg, R. B., Fischer, R. L., and Ohad, N. (2000) Mutations in the FIE and MEA Genes That Encode Interacting Polycomb Proteins Cause Parent-of-Origin Effects on Seed Development by Distinct Mechanisms.  Plant Cell, 12:12, 2367-81.  Seed Institute Article. doi: 10.1105/tpc.12.12.2367. [Download pdf file]
Apuya, N. R., Yadegari, R., Fischer, R. L., Harada, J. J., Zimmerman, J. L., and Goldberg, R. B. (2001) The Arabidopsis Embryo Mutant Schlepperless Has a Defect in the Chaperonin-60α Gene.  Plant Physiol., 126:2, 717-30.  Back Cover Article.  Seed Institute Article. doi: 10.1104/pp.126.2.717. [Download pdf file]
Goldberg, R.B. (2001) From Cot Curves to Genomics: How Gene Cloning Established New Concepts in Plant Biology., Plant Physiol., 125:1, 4-8. doi: 10.1104/pp.125.1.4. [Download pdf file]
Sanders, P. M., Lee, P. Y., Biesgen, C., Boone, J. D., Beals, T. P., Weiler, E. W., and Goldberg, R. B. (2000) The Arabidopsis DELAYED DEHISCENCE1 Gene Encodes an Enzyme in the Jasmonic Acid Synthesis Pathway. Plant Cell, 12:7, 1041-61. Cover Article. doi: 10.1105/tpc.12.7.1041. [Download pdf file]
Sanders, P. M., Bui, A. Q. , Weterings, K., McIntire, K. N., Hsu, Y-C., Lee, P. Y., Truong, M. T., Beals, T. P., and Goldberg, R. B. (1999) Anther Developmental Defects in Arabidopsis Thaliana Male-Sterile Mutants. Sex. Plant. Reprod., 11:6, 297-322. doi: 10.1007/s004970050. [Download pdf file]
Ohad, N., Yadegari, R., Margossian, L., Hannon, M., Michaeli, D., Harada, J. J., Goldberg, R. B., and Fischer, R. L. (1999) Mutations in FIE, a WD Polycomb Gene, Allow Endosperm Development Without Fertilization. Plant Cell, 11:3, 407-15. doi: 10.1105/tpc.11.3.407. [Download pdf file]
Kiyosue, T., Ohad, N., Yadegari, R., Hannon, M., Dinney, J., Wells, D., Katz, A., Margossian, L., Harada, J. J., Goldberg, R. B., and Fischer, R. L. (1999) Control of Fertilization-Independent Endosperm Development by the MEDEA Polycomb Gene in Arabidopsis. Proc. Natl. Acad. Sci. USA, 96:7, 4186-91. doi: 10.1073/pnas.96.7.4186. [Download pdf file]
Kinoshita, T., Yadegari, R., Harada, J. J., Goldberg, R. B., and Fischer, R. L. (1999) Imprinting of the MEDEA Polycomb Gene in the Arabidopsis Endosperm. Plant Cell, 11:10, 1945-52. Seed Institute Article. doi: 10.1371/journal.pgen.1000663. [Download pdf file]
Van Rhijn, P., Goldberg, R. B., and Hirsch, A. M. (1998) Lotus Corniculatus Nodulation Specificity Is Changed By the Presence of a Soybean Lectin Gene. Plant Cell, 10:8, 1233-49. Cover Article. doi: 10.1105/tpc.10.8.1233. [Download pdf file]
Lotan, T., Ohto, M., Yee, K. M., West, M. A. L., Lo, R., Kwong, R. W., Yamagishi, K., Fischer, R. L., Goldberg, R. B., and Harada, J. J. (1998) Arabidopsis LEAFY COTYLEDON1 is Sufficient to Induce Embryo Development in Vegetative Cells. Cell, 93:7, 1195-1205. Seed Institute Article. doi:10.1016/S0092-8674(00)81463-4. [Download pdf file]
Dunn, S. M., Drews, G. N., Fischer, R. L., Harada, J. J., Goldberg, R. B., and Koltunow, A. M.  (1997) First: An Arabidopsis Mutant With Altered Cell Division Planes and Radial Pattern Disruption During Embryogenesis. Sex. Plant. Reprod., 10:6, 358-67. Seed Institute Article. doi: 10.1007/s004970050. [Download pdf file]
Yadegari, R. and Goldberg, R. B. (1997) Embryogenesis in Dicotyledonous Plants. In: Cellular and Molecular Biology of Plant Seed Development, B. A. Larkins and I. K. Vasil, eds., Kluwer Press, pp. 3-52. doi: 10.1007/978-94-015-8909-3_1.
Beals, T. P. and Goldberg, R. B. (1997) A Novel Cell Ablation Strategy Blocks Tobacco Anther Dehiscence. Plant Cell, 9:9, 1527-45. Cover Article. doi: 10.1105/tpc.9.91527. [Download pdf file]
Goldberg, R. B., Sanders, P. M., and Beals, T. P. (1995) A Novel Cell- Ablation Strategy for Studying Plant Development. Phil. Trans. R. Soc., 350:1331, 5-17. doi: 10.1098/rstlb.1995.0131. [Download pdf file]
Yadegari, R., de Paiva, G. R., Laux, T., Koltunow, A. M., Apuya, N., Zimmerman, J. L., Fischer, R. L., Harada, J. J., and Goldberg, R. B. (1994) Cell Differentiation and Morphogenesis are Uncoupled in Arabidopsis Raspberry Embryos. Plant Cell, 6:12, 1713-29. Cover Article. doi: 10.1105/tpc.6.12.1713. [Download pdf file]
West, M. A. L., Yee, K. M., Dano, J., Zimmerman, J. L., Fischer, R. L., Goldberg, R. B., and Harada, J. J. (1994) LEAFY COTYLEDON 1 is an Essential Regulator of Late Embryogenesis and Cotyledon Identity in Arabidopsis.; Plant Cell, 6:12, 1731-45. Seed Institute Article. doi: 10.1105/tpc.6.12.1731. [Download pdf file]
Goldberg, R. B., de Paiva, G., and Yadegari, R. (1994) Plant Embryogenesis: Zygote to Seed. Science, 266:5185, 605-14. doi: 10.1126/science.266.5185.605. [Download pdf file]
Goldberg, R. B., Beals, T. P., and Sanders, P. M. (1993) Anther Development: Basic Principles and Practical Applications. Plant Cell, 5:10, 1217-29. doi: 10.1105/tpc.5.10.1217. [Download pdf file]
Perez-Grau, L., Goldberg, R.B. (1989) Soybean Seed Protein Genes are Regulated Spatially During Embryogenesis. Plant Cell, 1:11, 1095-1109. doi: 10.1105/tpc.1.11.1095. [Download pdf file]
Jofuku, K.D., Goldberg, R.B. (1989) Kunitz Trypsin Inhibitor Genes are Differentially Expressed During the Soybean Life Cycle and in Transformed Tobacco Plants. Plant Cell, 1:11, 1079-93. doi: 10.1105/tpc.1.11.1079. [Download pdf file]
Jofuku, K.D., Schipper, R.D., Goldberg, R.B. (1989) A Frameshift Mutation Prevents Kunitz Trypsin Inhibitor mRNA Accumulation in Soybean Embryos. Plant Cell, 1:4, 427-35. doi: 10.1105./tpc.1.4.427. Erratum in: Plant Cell, 1:5, 567. [Download pdf file]
Goldberg, R.B. (1988) Plants: Novel Developmental Processes. Science, 240:4858, 1460-67. [Download pdf file]
Barker, S.J., Harada, J.J., and Goldberg, R.B. (1988) Cellular Localization of Soybean Storage Protein mRNA in Transformed Tobacco Seeds. Proc. Natl. Acad. Sci. USA, 85:2, 458-62. [Download pdf file]
Walling, L., Drews, G.N., and Goldberg, R.B. (1986) Transcriptional and Posttranscriptional Regulation of Soybean Seed Protein Messenger-RNA Levels. Proc. Natl. Acad. Sci. USA, 83:7, 2123-27. [Download pdf file]
Okamuro, J.K., Jofuku, K.D., and Goldberg, R.B. (1986) Soybean Seed Lectin Gene and Flanking Nonseed Protein Genes are Developmentally Regulated in Transformed Tobacco Plants. Proc. Natl. Acad. Sci. USA, 83:21 8240-44. [Download pdf file]
Kamalay, J.C. and Goldberg, R.B. (1984) Organ-Specific Nuclear RNAs in Tobacco. Proc. Natl. Acad. Sci. USA, 81:9, 2801-5. [Download pdf file]
Kamalay, J.C. and Goldberg, R.B. (1980) Regulation of Structural Gene Expression in Tobacco. Cell, 19:4, 935-46. doi: 10.1016/0092-8674(80)90085-9. [Download pdf file]
Goldberg, R.B., Hoschek, G., Kamalay, J.C., and Timberlake, W.E. (1978) Sequence Complexity of Nuclear and Polysomal RNA In Leaves of the Tobacco Plant. Cell, 14:1,123-31. doi: 10.1016/0092-8674(78)90307-0. [Download pdf file]